Tiannan Guo received training of clinical medicine (1999 - 2006) at Tongji Medical College, Huazhong University of Science and Technology, and learned biology (2001 - 2005) at Wuhan University before he moved to Singapore for PhD training in cancer proteomics (2008 - 2012) in the laboratories of Dr. Newman Sze in Nanyang Technological University and Dr. Oi Lian Kon in National Cancer Centre Singapore. In 2012, Tiannan started his postdoctoral training in the laboratory of Dr. Ruedi Aebersold in ETH Zurich. Tiannan moved to Sydney as the Scientific Director of ProCan, group leader of Cancer Proteome, Children’s Medical Research Institute, and the conjoint senior lecturer at The University of Sydney Medical School, in March 2017. ​Tiannan joined the Westlake Institute for Advanced Studies, Westlake University in August 2017 as a tenure-track Assistant Professor, and was promoted to tenured Associate Professor in Jan 2023. He is the Director of iMarker lab (upgraded to Westlake Center for Intelligent Proteomics) at Westlake Laboratory in 2020, and an Associate Faculty Member of the Research Center for Industries of the Future at Westlake University. In Aug 2025, he was appointed as the founding Executive Vice Dean for School of Future Biomedicine at Westlake University. He also serves in multiple journals, including Molecular & Cellular Proteomics, Genomics Proteomics Bioinformatics, Cell Reports Medicine, and Cell Systems.